Statin Use Improves Recurrence-Free Survival in Stubborn Breast Cancer

Statin Use Improves Recurrence-Free Survival in Stubborn Breast Cancer
statins and breast cancerOne man's cholesterol-lowering drug may soon be another woman's breast cancer treatment. A report from the University of Texas MD Anderson Cancer Center demonstrated the efficacy of a statin (specifically, simvastatin) combined with radiation therapy in treating stubborn inflammatory breast cancer (IBC). "Our study showed for the first time that simvastatin combined with radiation improved the local recurrence-free survival rate of women with IBC, an aggressive variant of breast cancer with a dismal prognosis," stated Wendy Woodward, MD, PhD, who was principal investigator on the study published in Stem Cells Translational Medicine, entitled, "Simvastatin Radiosensitizes Differentiated and Stem-Like Breast Cancer Cell Lines and Is Associated With Improved Local Control in Inflammatory Breast Cancer Patients Treated With Postmastectomy Radiation" in a news article from Virtual Strategy Magazine. Dr. Woodward's team of researchers was interested in statin use with breast cancer due to a large retrospective study from Denmark. "Our curiosity was piqued by the Denmark study and we also began look
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