Predicting Breast Cancer Outcomes May Improve, Thanks To Promising, New Biomarker

Predicting Breast Cancer Outcomes May Improve, Thanks To Promising, New Biomarker
breast cancer biomarkerA group of researchers from McGill University in Montreal, Canada, have discovered a new protein, p66ShcA, which could become a reliable biomarker to identify breast cancers with poor prognoses. One of the most deadly characteristics of cancer cells is their capacity to metastasize, which means they can travel from their primary site of origin into other organs or tissues, giving rise to other malignant growths. In breast cancer, a process called epithelial to mesenchymal transition (EMT), whereby epithelial cells lining organ surfaces come into contact with the environment, can promote metastasis. This allows tumor cells to lose mature epithelial characteristics, and gain those of  mesenchymal cells, enabling them to move through the cellular matrix and into the blood stream, thus beginning their metastases to distant organs and tissues. In their study, entitled “p66ShcA Promotes Breast Cancer Plasticity by Inducing an Epithelial to Mesenchymal Transition” and published in the Molecular and Cellular Biology Journa
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.