Hispanic women who descend from indigenous Americans may have less probability of developing breast cancer than women from other ethnicities, according to a study conducted at the University of California, San Francisco (UCSF). The study found a genetic variant particularly common in these women lowers the risk dramatically.
In addition, the researchers were able to determine that about one in each five Latina women living in the United Stated carry at least one cope of that variant, and one percent carry two.
Even though the researchers haven't been able to fully understand the function of the genetic variant, the study demonstrated that women who carry the gene have less dense breast tissue, according to the mammograms conducted, which is a crucial factor in the development of the disease. The research team believes that the genetic variant may influence the production of estrogen receptors.
Focusing on the chromosome 6, the scientists found the protective variant, a single nucleotide polymorphism (SNP), was present in about 15 percent of women with Mexican descendant, 10 percent in Colombian and 5 percent in Puerto Rican. However, the frequency of SNP in either white and black women was only one percent and two percent in Chinese women.
“My expectation wo