Early Stage Breast Cancer Patients At Increased Risk of Leukemia After Treatment

Early Stage Breast Cancer Patients At Increased Risk of Leukemia After Treatment
shutterstock_222626152A recent study from a team of researchers at the Johns Hopkins Kimmel Cancer Center indicates that the risk of leukemia following radiotherapy or chemotherapy in early stage breast cancer is approximately two times higher than suggested by previous studies. The study entitled “Risk of Marrow Neoplasms After Adjuvant Breast Cancer Therapy: The National Comprehensive Cancer Network Experience” was recently published in the Journal of Clinical Oncology. Adjuvant therapy improves survival outcomes in patients with breast cancer. Although any negative impact on survival from therapy-related complications is already accounted for in the observed average improvements in disease-free survival (DFS) and overall survival (OS) after adjuvant therapy, some long-term complications such as leukemia can still occur. The research team analyzed data from the National Comprehensive Cancer Network (NCCN) Breast Cancer Outcomes and registered the frequency of marrow neoplasms (MNs) after a diagnosis of early-stage breast cancer in a cohort of 20,063 patients after a median follow-up of 5.1 years. Of these patients, 50 developed leukem
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