Major Advance Made in Understanding Breast Cancer Tumor Metastasis

Major Advance Made in Understanding Breast Cancer Tumor Metastasis
shutterstock_143266993A recent study by Albert Einstein College of Medicine researchers explains how breast cancer cells with low levels of profilin 1 protein have an increased ability to metastasize and invade other tissues. Researchers and medical professionals have been focused on developing new treatments that can stop cancer from spreading, as it often results in the death of patients suffering from this malignancy. Despite efforts by the scientific and medical community, no effective treatments have been advanced to stop or prevent tumor cells from spreading from its primary location -- a critical step in cancer, when it can spread and reach different organs, proliferating in different locations within the body. The study titled "Profilin 1 regulates invadopodium maturarion in human breast cancer cells" was published in the European Journal of Cell Biology, and reveals how profilin 1 influences the formation of some structures that determine tumor invasion. "To obtain this level of effectiveness the tumour cells form a subcellular structure called invadopodia (from the Latin
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