Mammogram Algorithm Improves Detection of Breast Cancer, Company Reports

Mammogram Algorithm Improves Detection of Breast Cancer, Company Reports

A researcher at Zebra Medical Vision who lost his wife to breast cancer has created a new mammography algorithm that uses machine and deep learning to diagnose breast cancer (BC), with results that the company claims are superior to those achieved using current methods.

mammogram using Zebra Medical Vision’s algorithm
Mammogram sample analyzed by Zebra Medical Vision’s algorithm.

Zebra’s mammography algorithm, developed with the aid of thousands of patient studies, aims to optimize BC screening by reducing both false positive results and false negative results. According to the company, this will lead to fewer unnecessary tests (a cost-savings measure) and lower stress for patients.

Doctors advise women over age 45 to be screened for BC every two years. Of these screenings, about 10 percent will be sent for specialized evaluation due to suspicious findings. But most women who undergo biopsies are found not to have cancer, while among the roughly  5 in every 1,000 who do develop breast cancer, one case of cancer is usually missed. In aiming for more accurate results, the Zebra algorithm may both protect women from unnecessary and possibly invasive tests, or from having a cancer that is left undetected.

The company’s chief medical officer, Dr. Eldad Elnekave, presented algorithm results at the recent SIIM Conference on Machine Intelligence in Medical Imaging (CMIMI 2016) in Virginia. He described the results as superior to those achieved by radiologists using state-of-the-art Computer Aided Detection methods for mammography, according to a press release.

“As a mammographer, I am cognizant of the vast variations in which breast cancer can manifest on a mammogram. Some of the most challenging cancer diagnoses are ones where the visual cues are not distinct lesions but rather regional asymmetry or architectural distortion in the breast tissue,” said Dr. Maya Cohen, director of both the Breast Health Center at Herzeliya Medical Center and of the imaging institute at Rabin Medical Center. “I welcome Zebra Medical Vision’s algorithm that is a new generation of mammography analysis, which can help us in the mission of finding even the most subtle cancers as early as possible.”

Zebra is adding the mammography algorithm to its list of clinical algorithms using machine and deep learning to read medical imaging in the fields of bone health, cardiovascular analysis, and liver and lung indications.

“We [use] machine and deep learning to help diagnose diseases responsible for the highest mortality rates, and breast cancer is one of the top on that list. We believe that the tool we’re providing to radiologists, as well as new algorithms which we continuously release, will help them deal with the continuous pressure they face to increase output and maintain high quality of care,” said Elad Benjamin, Zebra Medical Visions’ chief executive officer.

October is Breast Cancer Awareness month.