Compound in Vegetables and Herbs, Luteolin, May Prevent Triple-Negative Cancer from Spreading

Compound in Vegetables and Herbs, Luteolin, May Prevent Triple-Negative Cancer from Spreading
Luteolin, a natural compound found in some vegetables and herbs, may hold promise for preventing triple-negative breast cancers from spreading, according to recent research. In "Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells," researchers reported that luteolin prevented lung metastasis in triple-negative breast cancer mouse models. The study was published in Breast Cancer: Targets and Therapy, "Triple-negative breast cancers are cancer cells that lack three receptors targeted by current chemotherapy regimens. Because of this lack of receptors, common cancer drugs can't 'find' the cells, and doctors must treat the cancer with extremely aggressive and highly toxic treatment strategies," Salman Hyder, professor of biomedical sciences in the College of Veterinary Medicine at the University of Missouri, said in a press release. "Women with this type of breast cancer also frequently develop metastatic lesions that originate from drug-resistant cells. Therefore, safer therapeutic therapies that are more effective are being sought for this deadly type of cancer in women." The researchers saw that luteolin — a common flavonoid found in celery, broccoli, parsley, and thyme — could prevent breast cancer from progressing in mice by blocking the expression of VEGF, a major growth factor i
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