Removing Part of Breast Better than Mastectomy in Older Cancer Patients, Study Finds

Removing Part of Breast Better than Mastectomy in Older Cancer Patients, Study Finds
Breast conserving surgery combined with radiation, a treatment option called breast conserving therapy (BCT), is better than mastectomy in a subset of breast cancer patients, particularly older ones, according to a study. MirelleLagendijk, MD, presented the research, "Breast conserving therapy and mastectomy revisited: Breast cancer-specific survival and the influence of prognostic factors in 129,692 patients," at the European Cancer Congress 2017 Jan. 27-30 in Amsterdam. Lagendijk is with the Erasmus MC Cancer Institute's Department of Surgical Oncology in Rotterdam. In the past, randomized trials showed that BCT and mastectomy produced similar survival outcomes. But such trials often excluded older patients or those with diseases besides breast cancer. Including such patients in large, population-based groups could better represent patient outcomes, researchers decided. Breast conserving therapy involves removing part of a breast that has a tumor. Mastectomy involves removing the entire breast. Professor Sabine Siesling led a group that conducted a population-based study assessing the survival of all non-metastatic breast cancer patients in the Netherlands Cancer Registry who had been diagnosed between 1999 and 2012. Siesling is with the University of Twente in Lagendijk and the Netherlands Comprehensive Cancer Organisation (IKNL). His colleagues in the study were from other hospitals. The nearly 130,000 breast cancer patients included in the research were divide
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