Even Small Breast Tumors Can be Aggressive, and Patients Can Benefit from Chemotherapy, Study Shows

Even Small Breast Tumors Can be Aggressive, and Patients Can Benefit from Chemotherapy, Study Shows
While many doctors consider small tumors less harmful, new data from the international MINDACT breast cancer study suggests otherwise. In the study, nearly one in four early-stage breast cancer patients with tumors smaller than 1 cm — a little less than half an inch — had aggressive tumors and benefited from chemotherapy after surgery. Researchers will present the findings at the European Society for Medical Oncology Congress in Madrid,  Sept. 8-12. “Our results challenge the assumption that all small tumors are less serious and do not need adjuvant chemotherapy,” Dr. Konstantinos Tryfonidis, a researcher at the European Organisation for Research and Treatment of Cancer in Brussels, said in a press release. He was the study's lead author. MINDACT covered 6,693 women who had early-stage breast cancer between 2007 and 2011. The European Organisation for Research and Treatment of Cancer and Breast International Group conducted the study, which covered nine countries. A previous analysis showed that 46 percent of the women that Adjvant! Online had deemed at high risk of having their cancer recur were actually at low risk, and did not benefit from chemotherapy. The risk was assessed by the 70-gene signature test MammaPrint. Researchers decided to analyze the 826 patients in the MINDACT study who had a primary
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