Signatera Test for Residual Disease Will Be Used in New Phase 2 Breast Cancer Trial

Signatera Test for Residual Disease Will Be Used in New Phase 2 Breast Cancer Trial
Signatera, Natera’s personalized test to detect residual signs of cancer in people with solid tumors, will be used in an upcoming Phase 2 trial as a tool to identify patients with early HR-positive (hormone receptor-positive), HER2-negative (human epidermal growth factor 2-negative) breast cancer who are at high risk of cancer relapse. The test also will be used to monitor the response of participants who do test positive for signs of residual disease to a combination therapy of Pfizer’s Ibrance (palbociclib) and AstraZeneca’s Faslodex (fulvestrant). The trial, called DARE (NCT04567420), will be carried out in the U.S. at the Yale Cancer Center in Connecticut, through Criterium, doing business as Academic Breast Cancer Consortium (ABRCC). Enrollment is not yet active; more information will become available here<
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