Researchers from the Wellcome Trust Sanger Institute have identified a new gene linked to triple negative breast cancer (TNBC), which has one of the poorest prognoses and describes 20% of all breast cancers. Finding an association between BCL11A and TNBC is important, as according to study author Dr. Carlos Caldas, "Finding a novel gene that is active in cancer should also help in the search for new treatments."
Writing in the journal Nature Communications, Dr. Caldas was joined by lead author Dr. Walid Khaled and senior author Dr. Pentao Liu, as well as fellow collaborators at Wellcome Trust Sanger Institute and University of Cambridge. Their article, "BCL11A is a Triple-Negative Breast Cancer Gene with Critical Functions in Stem and Progenitor Cells," described experiments conducted with humans and mice to discover the presence of overactive BCL11A in up to 38% of High BCL11A Activity Found in Triple Negative Breast Cancer
Researchers from the Wellcome Trust Sanger Institute have identified a new gene linked to triple negative breast cancer (TNBC), which has one of the poorest prognoses and describes 20% of all breast cancers. Finding an association between BCL11A and TNBC is important, as according to study author Dr. Carlos Caldas, "Finding a novel gene that is active in cancer should also help in the search for new treatments."
Writing in the journal Nature Communications, Dr. Caldas was joined by lead author Dr. Walid Khaled and senior author Dr. Pentao Liu, as well as fellow collaborators at Wellcome Trust Sanger Institute and University of Cambridge. Their article, "BCL11A is a Triple-Negative Breast Cancer Gene with Critical Functions in Stem and Progenitor Cells," described experiments conducted with humans and mice to discover the presence of overactive BCL11A in up to 38% of