Updates

December 11, 2019December 11, 2019
FDA Approves FoundationOne CDx as Companion Diagnostic Test for Piqray Treatment

The U.S. Food and Drug Administration (FDA) has approved Foundation Medicine’s FoundationOne CDx as a companion diagnostic test for identifying advanced breast cancer patients ... Read more
December 9, 2019
HHS Grant to Advance Breast Cancer Screenings Based on Ultrasound

A U.S. Department of Health and Human Services grant will fund research at two universities into whether an ultrasound technology might be more effective than ... Read more
December 6, 2019
CHMP Favors Kadcyla Approval in EU for Certain HER2-positive Early Breast Cancer Patients

The Committee for Medicinal Products for Human Use (CHMP), an arm of the European Medicines Agency, has recommended that Kadcyla (ado-trastuzumab emtansine) be approved as ... Read more
December 4, 2019
Weight Loss Surgery May Lower Risk of Breast Cancer, Research Suggests

Weight loss surgery may reduce the risk of developing breast cancer in obese individuals, even among those with a genetic predisposition towards cancer, new ... Read more
November 15, 2019November 15, 2019
More Than $850M Raised for Inflammatory Breast Cancer Research

Susan G. Komen, the Inflammatory Breast Cancer (IBC) Research Foundation, and the Milburn Foundation have joined to raise more than $850,000 for research ... Read more

News

Fertility Clinics and Breast Cancer ‘Previvor’ Team Up to Raise Awareness About Genetic Risk of Disease
November 13, 2019
For patients with gene mutations that increase their risk for diseases such as breast ...
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Blood Test May Identify Breast Cancer Years Before Symptoms Appear, Pilot Study Suggests
November 11, 2019November 11, 2019
A simple blood test – which measures antibodies against certain tumor proteins, or antigens ...
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Most Breast Cancers Found by Hand, MammaCare Researchers Say
November 8, 2019November 8, 2019
Decades after establishing the recognized standard for performing and teaching clinical and personal breast ...
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First Patient Dosed in Phase 3 Trial of Tucatinib-Kadcyla Combo for Advanced HER2-Positive Breast Cancer
November 6, 2019
A Phase 3 trial exploring a combination of Seattle Genetics‘ tucatinib plus standard Kadcyla ...
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Hormone Therapy Has More Long-term Impact on Quality of Life Than Chemo, Study Suggests
November 4, 2019
Challenging conventional wisdom, new findings suggest that hormone therapy may have a greater impact ...
News

Pathologist Creates Program Allowing Patients to Face Their Cancer Head-on
November 1, 2019
Massachusetts pathologist Lija Joseph, MD, has created an innovative program that allows patients, including ...

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Seattle Genetics’ Tucatinib Extends Survival Outcomes in Metastatic HER2-positive Breast Cancer Patients, Phase 2 Trial Shows
October 30, 2019
People with HER-positive advanced breast cancer who received multiple HER-targeted therapies have significantly better ...
FDA Supports Use of Anti-diarrheal Medications with Nerlynx
October 28, 2019October 28, 2019
The U.S. label of Nerlynx (neratinib), a treatment for early stage HER2-positive breast cancer, now includes ...
Bempegaldesleukin-Opdivo Combo Leads to Prolonged Responses in TNBC Patients, Phase 1/2 Trial Shows
October 25, 2019November 11, 2019
Daiichi Sankyo Files New Drug Application for DS-8201 in Japan
October 23, 2019October 24, 2019
Trastuzumab Deruxtecan Gets FDA Priority Review for Metastatic HER2-Positive Breast Cancer
October 21, 2019October 24, 2019
Keytruda-chemo Combo Best for Clearing Tumors in Early TNBC, Latest Trial Data Show
October 18, 2019October 28, 2019

Kisqali-Faslodex Combo Prolongs Survival of Postmenopausal Women with Advanced Breast Cancer, Phase 3 Trial Shows
October 16, 2019
Kisqali (ribociclib) in combination with Faslodex (fulvestrant) prolongs the survival of postmenopausal women with ...
Hormone Therapy-Chemo Combo Reduces Risk of Tumor Return in Highly Recurrent Breast Cancer, Phase 3 Trial Shows
October 14, 2019October 14, 2019
Terranea Resort Turns Pink for National Breast Cancer Awareness Month
October 9, 2019
Veliparib-Chemo Combo Prolongs Survival Without Disease Progression in Certain Advanced Breast Cancer Patients, Phase 3 Trial Shows
October 7, 2019

Verzenio-Faslodex Combo Prolongs Survival of Women with Advanced Breast Cancer, Phase 3 Trial Shows
October 4, 2019October 7, 2019
Verzenio (abemaciclib) in combination with Faslodex (fulvestrant) prolongs the survival of women with HR-positive, ...
PINKTOBER Events at Hard Rock Promote Breast Cancer Awareness
October 2, 2019
First Patients Dosed in Phase 1 Trial Testing ARV-471 in Advanced, ER-Positive Breast Cancer
September 30, 2019

News

Mylan Launches Generic Version of Faslodex Injection in the US
September 27, 2019October 16, 2019
The U.S. Food and Drug Administration has approved Mylan‘s generic version of AstraZeneca‘s Faslodex ...
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For Breast Cancer Awareness Month, Life Image Offering Free Access to Mammosphere App
September 25, 2019October 7, 2019
Because access to prior mammograms is critical for women during all stages of breast ...
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New Herceptin-Perjeta Formulation Shows Promising Safety and Pharmacokinetic Profile, Phase 3 Trial Shows
September 23, 2019
When given together with Herceptin (trastuzumab) at a fixed dose through an under-the-skin (subcutaneous) ...
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FDA OKs Use of Tool to Predict Patient Response to New Form of Cisplatin in Planned Phase 3 Study
September 20, 2019September 20, 2019
The U.S. Food and Drug Administration (FDA) has approved use of a device, called ...
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Herceptin Developers Granted 2019 Lasker-DeBakey Research Award
September 18, 2019
The 2019 Lasker-DeBakey Clinical Medical Research Award has been granted to scientists H. Michael Shepard, ...
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TNBC Patient Given Investigative Antibody, Leronlimab, Under Emergency Exception
September 16, 2019
A metastatic triple-negative breast cancer (TNBC) patient is being treated with CytoDyn’s investigational leronlimab ...
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FDA to Review Nerlynx Combo as Third-line Treatment for HER2-positive Metastatic Breast Cancer
September 13, 2019September 13, 2019
The U.S. Food and Drug Administration (FDA) has agreed to review Puma Biotechnology’s application seeking ...
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Music Helps Ease Pain and Fatigue of Breast Cancer, Study Shows
September 11, 2019
Listening to music at home can considerably ease the severity of symptoms related to ...
A Lump in the Road - A Column by Nancy Brier, Columns

Cancer by the Numbers
September 10, 2019September 5, 2019
1: Number of times a doctor told me, “Best-case scenario, you’ll be stuck with ...
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Nerlynx Granted FDA’s Orphan Drug Status for Treating Breast Cancer with Brain Metastases
September 9, 2019September 9, 2019
The U.S. Food and Drug Administration (FDA) has granted orphan drug status to Puma Biotechnology’s Nerlynx (neratinib) for ...
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Longer Use of Hormone Replacement Therapy Linked to Greater Breast Cancer Risk in Study
September 6, 2019
The longer women use hormone therapy after menopause the higher is their breast cancer ...
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FDA Urges Inclusion of Men in Clinical Trials for Breast Cancer Treatment
September 4, 2019
The U.S. Food and Drug Administration (FDA) has drafted a series of recommendations urging ...
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Tecentriq-Abraxane Combo OK’d in EU to Treat Certain Advanced Triple-negative Breast Cancers
August 30, 2019
The European Commission has approved the use of Roche‘s Tecentriq (atezolizumab) in combination with Abraxane (nab-paclitaxel) ...
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USPSTF Updates Recommendations on Testing for BRCA-related Cancers in Women
August 28, 2019
The United States Preventive Services Task Force (USPSTF) has revised their recommendations on testing ...
A Lump in the Road - A Column by Nancy Brier, Columns

10 Commandments for Surviving Breast Cancer
August 27, 2019August 22, 2019
I hate giving advice, but I’ve learned lessons through my breast cancer journey that ...
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Grant to Fund CAR T-cell Trial for HER2-Positive BC with Brain Metastases
August 26, 2019September 18, 2019
The California Institute for Regenerative Medicine (CIRM) has granted a $9.28 million award to ...
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Oral Paclitaxel Combo Leads to Better Response Rates Than IV Therapy in MBC, Data Shows
August 23, 2019August 23, 2019
Treatment with a combination of oral paclitaxel and encequidar led to higher and stronger ...
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FDA Approves Rozlytrek for Breast Cancer, Other Solid Tumors with Specific Gene Defect
August 21, 2019
The U.S. Food and Drug Administration (FDA) has approved Rozlytrek (entrectinib) as an oral ...

June 22, 2018June 22, 2018

Clinical Trial of Tamoxifen-based Gel in Reducing Breast Density Recruiting in US, EU

News

The ability of a gel containing a tamoxifen-byproduct to reduce breast density — associated with an increased risk of breast cancer — is now being evaluated in a recruiting Phase 3 clinical trial. Approximately half of women in ... Read more

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