Scientists Find Important Target for Triple-Negative Breast Cancer

sutdy target breast cancer A research team found a target for triple-negative breast tumors, a common and aggressive type of breast cancer. The study resulted from a collaboration between scientists at the University of California at Berkeley, UC San Francisco, and Boston College, who discovered that the subtype of cancer relies on fat as an energy source, which is thought to be a first step for the development of a new and more effective treatment option for patients with triple-negative breast tumors. Researchers identified the target called GSTP1 and used a molecule similar to a drug to address the vulnerability and eliminate cancer cells in the lab. The investigation was able to shrink tumors in mice. “We were looking for targets that drive cancer metabolism in triple-negative breast cancer, and we found one that was very specific to this type of cancer,” said Daniel K. Nomura, an associate professor of chemistry and of nutritional sciences and toxicology at UC Berkeley, in a press release. Nomura is also the senior author for the study, titled "GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity," which was recently published in Cell Chemical Biology
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