Partial Breast Radiation Therapy May Effectively Prevent Cancer Relapse, Trial Shows

Partial Breast Radiation Therapy May Effectively Prevent Cancer Relapse, Trial Shows
Accelerated partial breast irradiation, a therapy that delivers higher doses of radiation over a shorter period of time and targets only the part of the breast where the tumor was removed, is as effective as whole-breast irradiation at preventing breast cancer recurrence, a trial showed. The results, "RAPID: A randomized trial of accelerated partial breast irradiation using 3-dimensional conformal radiotherapy (3D-CRT)," were presented at the 2018 San Antonio Breast Cancer Symposium. After a lumpectomy — a surgery that removes the breast tumor and some of the surrounding tissue — a patient is often given radiation to kill the remaining cancer cells to help prevent the tumor from recurring. Traditionally, this has been done with whole-breast irradiation (WBI) which, as the name implies, is when the whole breast receives radiation. This is often done over a three- to six-week period, which can be inconvenient for patients. Accelerated partial breast irradiation (APBI) involves giving a larger dose of radiation to the area of the breast where the tumor was removed, with a margin of normal tissue to make sure that all cancer cells are caught. Because the dose is more concentrated, this treatment can take less than a week. The goal of the RAPID clinical trial (NCT00418210) was to determine whether APBI was as effective
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