Posts by: Margarida Azevedo, MSc

News

Herzuma, a biosimilar to Genentech‘s Herceptin (trastuzumab), is now available in the U.S. for the same indications as the reference therapy, including for the treatment of HER2-positive breast cancers and stomach cancers. The ... Read more

May 25, 2016May 25, 2016

Levels of Protein, MCJ, May Predict Chemo Resistance and Relapse Risk in Breast Cancer Patients

News

Breast cancer patients with low expression of a specific protein, methylation-controlled J protein (MCJ), may be resistant to chemotherapy treatments and at high risk of relapse, according to a retrospective study ... Read more

May 18, 2016May 18, 2016

Accelerated Partial Breast Radiation vs Whole Breast Radiation Equal Against Breast Cancer

News

Promising results from the Groupe Européen de Curiethérapie European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) trial, to evaluate the effects of partial breast irradiation (PBI) administered with multicatheter interstitial brachytherapy, were ... Read more

April 29, 2016April 29, 2016

Agendia’s Genomic Risk Assay Cuts Need for Chemotherapy in Early Breast Cancer Patients by 46% in Phase 3 Trial

News

Agendia, Inc., announced initial positive results of a clinical trial investigating a genomic assay’s ability to accurately predict the need for chemotherapy in early stage breast cancer patients thought at risk of disease reoccurrence. The ... Read more

April 22, 2016October 18, 2016

Cartilage Protein Linked in Study to Aggressive, Metastatic Breast Cancer

News

A protein found mainly in cartilage tissue, called the Cartilage Oligomeric Matrix Protein (COMP), is present at high levels in patients with a poor breast cancer prognosis, and in animal studies contributed to ... Read more

April 12, 2016April 13, 2016

Statin May Block Protein Pathway That Promotes Breast Cancer, Study Reports

News

A metabolic pathway that is upregulated in some breast cancers promotes disease progression by activating a specific cell signaling protein called Arf6, a study reported. But the researchers, working in a ... Read more

April 11, 2016April 11, 2016

New Study of Scout Breast Lesion Guidance System Shows Clinical Efficacy, High Patient Satisfaction

News

Positive data from a study evaluating the clinical effectiveness and clinician and patient satisfaction of the SAVI Scout breast localization and surgical guidance system was recently announced by Cianna Medical. The results were ... Read more

March 31, 2016March 31, 2016

MD Anderson Researchers Develop Neo-Bioscore, a More Refined Breast Cancer Staging System

News

Researchers at the University of Texas MD Anderson Cancer Center have developed a novel breast cancer staging system called Neo-Bioscore which includes HER2 status of the tumor. This approach is built on ... Read more

March 23, 2016March 23, 2016

HER2 Positive Breast Cancers Drastically Reduced Before Surgery with 2-Drug Combo, Study Shows

News

A clinical trial funded by Cancer Research UK indicates that a drug combination of lapatinib, a protein tyrosine kinase inhibitor, and trastuzumab, a monoclonal antibody, before surgery can quickly shrink and even ... Read more

March 16, 2016March 16, 2016

Study Identifies a Protein in Breast Cells That Protects Against Cancer’s Spread

News

Researchers have discovered that a key protein, ROBO1, is essential for the cellular response to extracellular matrix changes that occur as a consequence of breast cancer progression. Moreover, its upregulation acts as ... Read more