Herzuma, a biosimilar to Genentech‘s Herceptin (trastuzumab), is now available in the U.S. for the same indications as the reference therapy, including for the treatment of HER2-positive breast cancers and stomach cancers. The ... Read more
Breast cancer patients with low expression of a specific protein, methylation-controlled J protein (MCJ), may be resistant to chemotherapy treatments and at high risk of relapse, according to a retrospective study ... Read more
Promising results from the Groupe Européen de Curiethérapie European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) trial, to evaluate the effects of partial breast irradiation (PBI) administered with multicatheter interstitial brachytherapy, were ... Read more
Agendia, Inc., announced initial positive results of a clinical trial investigating a genomic assay’s ability to accurately predict the need for chemotherapy in early stage breast cancer patients thought at risk of disease reoccurrence. The ... Read more
A protein found mainly in cartilage tissue, called the Cartilage Oligomeric Matrix Protein (COMP), is present at high levels in patients with a poor breast cancer prognosis, and in animal studies contributed to ... Read more
A metabolic pathway that is upregulated in some breast cancers promotes disease progression by activating a specific cell signaling protein called Arf6, a study reported. But the researchers, working in a ... Read more
Positive data from a study evaluating the clinical effectiveness and clinician and patient satisfaction of the SAVI Scout breast localization and surgical guidance system was recently announced by Cianna Medical. The results were ... Read more
Researchers at the University of Texas MD Anderson Cancer Center have developed a novel breast cancer staging system called Neo-Bioscore which includes HER2 status of the tumor. This approach is built on ... Read more
A clinical trial funded by Cancer Research UK indicates that a drug combination of lapatinib, a protein tyrosine kinase inhibitor, and trastuzumab, a monoclonal antibody, before surgery can quickly shrink and even ... Read more
Researchers have discovered that a key protein, ROBO1, is essential for the cellular response to extracellular matrix changes that occur as a consequence of breast cancer progression. Moreover, its upregulation acts as ... Read more
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