HER2

December 21, 2020December 21, 2020

Margenza Approved in US for Pretreated HER2-positive Breast Cancer

News

Margenza (margetuximab-cmkb), in combination with chemotherapy, has been approved in the U.S. to treat adults with metastatic HER2-positive breast cancer who have previously received two or more anti-HER2 regimens, at ... Read more

June 8, 2020June 8, 2020

Merck to Launch Ontruzant, a Herceptin Biosimilar, in US

News

Ontruzant (trastuzumab-dttb), a biosimilar to Genentech‘s Herceptin (trastuzumab), will now be made available in the U.S. as a treatment for HER2-overexpressing breast cancers as well as for stomach cancers, according to a ... Read more

February 15, 2019February 18, 2019

Experimental Compound Could Broaden HER2-targeted Approach to BC

News

By targeting small regulatory molecules called microRNAs (miRNAs), researchers were able to reprogram breast cancer cells and render them sensitive to HER2-targeting medicines, such as Herceptin (trastuzumab) and Kadcyla (ado-trastuzumab emtansine), a study ... Read more

December 3, 2018

Planned Phase 2 Trial to Test Vaccine in Triple-negative Breast Cancer Patients, Generex Says

News

Generex Biotechnology has entered into an agreement with the NSABP Foundation to manage a possible Phase 2 clinical trial testing an anti-cancer vaccine in patients with metastatic triple negative breast cancer. ... Read more

February 1, 2018

Patient Dosing Begins in Phase 2 Trial of MCLA-128 in Metastatic Breast Cancer

News

The first patient in the Phase 2 clinical study of MCLA-128 in metastatic breast cancer patients has been dosed, The Netherlands-based immuno-oncology company Merus recently announced. The international study (NCT03321981) ... Read more

January 22, 2018

MammaTyper Test Able to Identify Women at Low Risk of Breast Cancer Spreading, Studies Show

News

BioNTech Diagnostics’ MammaTyper test lets doctors determine the type of breast cancer a woman has and identify patients at low risk of having their cancer spread. The company discussed the diagnostic test’s ... Read more

May 8, 2017

Regular Use of Low-Dose Aspirin May Lower Risk of Women’s Breast Cancer, Study Reports

News

Regular use of low-dose baby aspirin reduces the risk of women’s breast cancer, according to the first research to reach such a conclusion. Aspirin is already known to reduce the risk ... Read more

November 1, 2016November 1, 2016

Herceptin Seen as Effective and Cost-Effective for ‘Worst-Case’ Early Breast Cancers in Study

News

Depending on the disease characteristics and age of a women with early stage but aggressive breast cancer, the cost-effectiveness of Herceptin (trastuzumab) may vary widely, according to a recent study ... Read more

October 17, 2016

Researchers Develop Vaccines to Fight HER2-Positive Breast Cancers

News

Vaccines containing specific molecules expressed by breast cancer cells can alert the immune system for the presence of the cells and trigger a response to eliminate them, according to a study ... Read more

September 12, 2016October 18, 2016

Circulating Breast Cancer Cells Can Switch HER2 Gene On-Off to Evade Treatment

News

In women with metastatic breast cancer who have gone through several rounds of treatment, circulating tumor cells can switch on and off a gene called HER2, allowing them to better ... Read more