The Role Of Cytokines In Breast Cancer

The Role Of Cytokines In Breast Cancer
shutterstock_178384334A recent review, published in the Journal of Interferon & Cytokine Research (JICR), titled "The Role of Cytokines in Breast Cancer Development and Progression", discussed the involvement of inflammation and the immune system in the development and progression of breast cancers. In particular, the role of cytokines has been a central focus in breast cancer research, due to their involvement in cancer initiation, protection, and metastasis. Cytokines are proteins secreted by the immune system that can control communication between immune cells and balance the intensity of an immune response. Cytokines are grouped, depending on their cellular function, into tumor necrosis factors, interleukins, interferons, and colony-stimulating factors. Even though over the years cytokines have been implied in cancer biology, their exact role in breast cancer is still not known. However, inflammation has been shown to play a major role in the development of several different cancers, promoting angiogenesis and metastasis, in which cytokines are known to play a crucial part. Th
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