Poor Prognosis for Breast Cancers Diagnosed After Negative Screening Mammography

Poor Prognosis for Breast Cancers Diagnosed After Negative Screening Mammography
While occurring at low rates, breast cancer cases diagnosed after a negative mammography screening are linked to poorer prognosis compared to those diagnosed after a positive mammogram, an observational study suggests. These findings highlight the need to improve early detection for these women. The study, “Breast Cancer With a Poor Prognosis Diagnosed After Screening Mammography With Negative Results,” was published in the journal JAMA Oncology. Interval breast cancers are those diagnosed between screening mammographies. In these patients, the last screening mammography came out negative. These cases represent approximate 15 percent of all breast cancers. Interval breast cancers include cancers that were missed on examination, as well as rapidly growing cancers, which tend to have poorer prognosis. Thus, identifying women at risk of breast cancer with a poor prognosis despite regular screening mammography could improve screening approaches for such patients. For this study, researchers evaluated women who developed breast cancer after a negative screening in an attempt to determine risk factors for the development of such cancers. They examined data from 306,028 women, 40 years or older, who underwent mammography screening between 2011 and 2014. The data was obtained from the Population-Based Research Optimizing Screening Through Personalized Regimens (PROSPR) consortium, which includes data from four centers – the Dartmouth Hitchcock Medical Center
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One comment

  1. Imani Crowell says:

    I wholeheartedly agree. In November of 2017 I had my first 3D mammogram that was NEGATIVE. In July of 2018 less than 8 months later I found a suspicious lump in my left breast and was sent for another mamo by another facility and found a positive cancer for ER Positive. In September , I had a biopsy (positive), a PET scan and in October (Breast Cancer Awareness Month) I had an Oncotype test and subsequently a mastectomy. My ONCO came back with a low score and I will have to have Chemo in a pill form for at least five years.
    I caution anyone to not rely on mamos alone and do a self-exam on a regular basis.
    I am 71 years old and feel that I made the correct decision to have it removed. However, I won’t do reconstruction and will look at getting a tattoo in about a year from now to cover the scars.

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