Posts by: Patricia Inacio, PhD

Breast Cancer News, in an email exchange, interviewed Dr. William Audeh, chief medical officer of Agendia and a breast medical oncologist with nearly 30 years of clinical practice experience, to know ... Read more

May 5, 2017May 8, 2017

MammaPrint Genomic Test Helps Early Stage Cancer Patients Safely Avoid Chemo, Agendia’s CMO Says

News

A genomic test, evaluated in several clinical trials and approved for use in the U.S. and Europe, can effectively tell early stage breast cancer patients what is their risk of cancer ... Read more

May 3, 2017

COMET Trial Now Recruiting to Study Active Surveillance in Low-risk DCIS

News

A new breast cancer clinical trial called COMET (NCT02926911) is now enrolling participants to evaluate the risks and benefits of a monitoring approach vs. a full-mode attack with surgery ... Read more

April 5, 2017April 5, 2017

New Drug Loaded into Nanoparticle Kills Cells in Aggressive Breast Cancer, U.K. Study Shows

News

Researchers in Great Britain have developed a potential new drug to target highly aggressive “triple negative” breast cancer (TNBC) — as well as a biodegradable nanoparticle to deliver it directly ... Read more

July 27, 2016July 27, 2016

Gene Mutations in Breast and Ovarian Cancer Promote Resistance to Therapy, Studies Say

News

Two new studies published in the Journal of Clinical Investigation revealed the mechanisms by which certain BRCA1 mutations make breast and ovarian cancers resistant to treatments. These new findings may help ... Read more

July 22, 2016July 22, 2016

Breast Cancer Gene Seen to Respond in Polar Ways, Either Promoting or Inhibiting Tumors

News

Researchers in Singapore have discovered how the gene EZH2, known to promote several types of cancer, is activated in breast cancer and lymphomas. Their findings, which may lead to new and ... Read more

May 1, 2015May 1, 2015

Researchers Discover Sequence in HER2 Protein Responsible For Cancer Cell Proliferation

Breast Cancer News, News

In a new study entitled “Blockade of a Key Region in the Extracellular Domain Inhibits HER2 Dimerization and Signaling,” researchers discover a key sequence in HER2 protein that, once ... Read more

March 16, 2015March 16, 2015

Mechanisms Behind Cell Metabolism in Response to Breast Cancer Drugs

News

In a new study entitled “Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies” researchers discovered a factor, the ubiquitin ligase RNF5, that regulates ... Read more

March 12, 2015March 12, 2015

Epstein-Barr Virus and HPV highly Prevalent in Aggressive Breast Cancer

Breast Cancer News, News

In a recent article entitled “Prevalence of Papillomaviruses, Polyomaviruses, and Herpesviruses in Triple-Negative and Inflammatory Breast Tumors from Algeria Compared with Other Types of Breast Cancer Tumors,” authors report ... Read more

March 9, 2015March 9, 2015

Breast Cancer Cells’ Shapes Modulate Body Inflammatory Response

Breast Cancer News, News

In a new study entitled “Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells” researchers show how tumor cells’ shape impacts their ... Read more