ER-positive breast cancer

September 23, 2016

Breast Cancer Patients with No Uterine Abnormalities Can Safely Use Nolvadex Therapy, Study Finds

News

A new study may help to reassure groups of breast cancer patients concerned that treatment with Nolvadex (tamoxifen) will increase their risk of endometrial, or uterine, cancer. The study, “Randomized trial of medroxyprogesterone acetate for ... Read more

June 7, 2016June 8, 2016

All About ER Positive, HER2 Negative Breast Cancer

News

About one in eight women in the United States will develop breast cancer, according to commonly used statistics. But other reports indicate that breast cancer rates are on the decline, likely ... Read more

February 24, 2015October 18, 2016

Researchers Discover Important Genetic Variant Linked to Breast Cancer Risk

News

A study published in the latest edition of the journal Human Molecular Genetics used fine-mapping analysis of genetic data to assess the association between individual genetic variations among patients and ... Read more

January 20, 2015January 20, 2015

ER-Positive Luminal B Breast Cancers and Body Mass Index Inversely Associated With HER2 Expression

Breast Cancer News, News

A recent study on genomic and transcriptomic profiling of luminal B breast cancer entitled “Anthropometric, metabolic and molecular determinants of human epidermal growth factor receptor 2 expression in luminal b ... Read more

January 13, 2015January 13, 2015

New Breast Cancer Prognostic Signature Identified

Breast Cancer News, News

A new study identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer. The work entitled “E2F4 regulatory program predicts patient survival prognosis in ... Read more

December 22, 2014October 18, 2016

Pfizer’s Palbociclib Doubles Progression-Free Survival in Breast Cancer Trial

Breast Cancer News, News

An experimental drug known as palbociclib, developed by Pfizer, Inc. and tested at the Revlon/UCLA Women’s Cancer Research Program in UCLA’s Jonsson Comprehensive Cancer Center (JCCC), extended progression-free survival of ... Read more

December 17, 2014December 17, 2014

Three Different Studies Target Androgen Receptors in Breast Cancer

News

During the 2014 San Antonio Breast Cancer Symposium, three studies presented by researchers from the University of Colorado Cancer Center showed the outcomes of androgen receptor blockade in breast cancer. ... Read more

December 1, 2014December 1, 2014

Study Finds Gene Linked to Tamoxifen Resistance in Breast Cancers

News

In a recent study published in the Proceedings of the National Academy of Sciences, a team of researchers from the Johns Hopkins Kimmel Cancer Center found a gene, MACROD2, which ... Read more

October 14, 2014October 16, 2014

Pfizer’s Palbociclib Granted FDA Priority Review For ER+ Breast Cancer Treatment

News

Pfizer Inc. has announced that the New Drug Application (NDA) for palbociclib has been accepted for filing and granted Priority Review by the United States Food and Drug Administration (FDA). ... Read more

August 14, 2014August 14, 2014

Aspirin May Help Prevent Breast Cancer In Overweight, Obese Women

Breast Cancer News, News

Over the last few years, evidence has been accumulating in the research community suggesting that obese or overweight women have a higher risk to develop breast cancer alongside decreased susceptibility ... Read more