Exercise Seen to Ease Some Effects of Aromatase Inhibitors in Breast Cancer Patients

Exercise Seen to Ease Some Effects of Aromatase Inhibitors in Breast Cancer Patients
A combination of resistance and aerobic exercise may lessen the side effects of aromatase inhibitors enough to keep breast cancer patients on this therapy, and certainly improves their overall health, researchers reported. The study, “The effect of exercise on body composition and bone mineral density in breast cancer survivors taking aromatase inhibitors,” was published in the Obesity Journal. Aromatase inhibitors (AIs), which lower estrogen production, are commonly used as an adjuvant therapy (given before surgery) in breast cancer treatment, especially in postmenopausal women with estrogen receptor-positive cancer. AIs are known to reduce the risk of breast cancer recurrence. But they can lead to severe side effects, such as bone loss or severe joint pain (arthralgia). Research has shown that nearly 40 percent of breast cancer survivors quit taking AIs before the end of their recommended five-year use. Gwendolyn Thomas, assistant professor of exercise science at Syracuse University, and colleagues at Yale, Penn State, Columbia, and the Dana-Faber Cancer Institute in Boston examined the effects of 12 months of aerobic and resistance exercise, compared to usual care, on changes in body composition in postmenopausal breast cancer patients taking AIs. In the Hormones and Physical Exercise (HOPE) trial (NCT02056067), a study funded by the National Institute of Health (NIH), 121 of these women were randomized to either supervised twice-weekly resistance exercise training and 150 minutes of weekly aerobic exercise, or to usual ca
Subscribe or to access all post and page content.

One comment

  1. wendy dickson says:

    would be interested in participating in study. Have been diagnosed with stage 2 breast cancer, and will probably be taking aromatase drug.i am a Huntsman World Senior Games Hall of Fame athlete in track and field. I work out 6 days a week with weights or anaerobic track exercises. my diet is excellent and I am lean and strong:probably in top 1% of 76 yr. old women in the world.

Leave a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.