Breast Cancer News

January 26, 2015

High Insulin Levels May Contribute to Increased Breast Cancer Risk

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Women have all the more reason to eat a healthy diet and to exercise regularly in order to maintain normal weight and insulin levels. A study from Imperial College London ... Read more

January 20, 2015January 20, 2015

ER-Positive Luminal B Breast Cancers and Body Mass Index Inversely Associated With HER2 Expression

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A recent study on genomic and transcriptomic profiling of luminal B breast cancer entitled “Anthropometric, metabolic and molecular determinants of human epidermal growth factor receptor 2 expression in luminal b ... Read more

January 14, 2015January 14, 2015

High BCL11A Activity Found in Triple Negative Breast Cancer

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Researchers from the Wellcome Trust Sanger Institute have identified a new gene linked to triple negative breast cancer (TNBC), which has one of the poorest prognoses and describes 20% of ... Read more

January 13, 2015January 13, 2015

New Breast Cancer Prognostic Signature Identified

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A new study identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer. The work entitled “E2F4 regulatory program predicts patient survival prognosis in ... Read more

December 29, 2014December 29, 2014

UCLA Laboratory Detects Breast Cancer with Novel Lens-Free Microscope

Breast Cancer News

Researchers at the University of California, Los Angeles (UCLA) have harnessed the power of large and expensive microscopes for cancer detection into the world’s first lens-free microscope. The device can ... Read more

December 26, 2014December 26, 2014

TLR5 Polymorphism Enhances Luminal Breast Cancer Progression

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Certain common DNA variations, called polymorphisms, can determine how tumor progression evolves in breast cancer and other types of cancers, including ovarian cancer. Researchers at The Wistar Institute, led by ... Read more

December 22, 2014October 18, 2016

Pfizer’s Palbociclib Doubles Progression-Free Survival in Breast Cancer Trial

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An experimental drug known as palbociclib, developed by Pfizer, Inc. and tested at the Revlon/UCLA Women’s Cancer Research Program in UCLA’s Jonsson Comprehensive Cancer Center (JCCC), extended progression-free survival of ... Read more

December 16, 2014December 16, 2014

Reevaluation of CYP2D6 Genotyping May Open Tamoxifen Treatment to More Breast Cancer Patients

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Despite clinical recommendations against using Cytochrome P450 2D6 (CYP2D6) gene expression as a guide for tamoxifen therapy for breast cancer patients, a study from the Mayo Clinic suggests otherwise. The ... Read more

December 15, 2014December 15, 2014

Alternate Biomarker Necessary for HER2 Breast Cancer Prognoses

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Despite the utility of certain biomarkers in predicting triple negative breast cancer outcomes after chemotherapy treatment, it appears as though the level of tumor-infiltrating lymphocytes (S-TILs) cannot predict the outcome ... Read more

December 12, 2014December 12, 2014

miR-21 Serves as Prognostic Biomarker in Triple-Negative Breast Cancer

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Patients with triple-negative breast cancer (TNBC), or those individuals with breast cancer cells that do not express estrogen, progesterone, or human epidermal growth factor receptor 2 receptors (ER-/PR-/HER-), may be ... Read more