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January 30, 2019

Mathematical Model Calculates Breast Cancer Risk in Women

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Researchers developed a mathematical model to calculate breast cancer risk in women, based on family history and genetics. According to investigators, this model not only allows the identification of women ... Read more

January 28, 2019

Breast Cancer Cells Can Be Turned into Harmless Fat Cells in Mice, Study Shows

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With the right molecular cues, breast cancer cells can be converted into harmless fat cells, preventing tumors from progressing and spreading, a study in mice shows. The study, “Gain Fat-Lose ... Read more

January 25, 2019

FDA Wants More Data Before Sacituzumab Govitecan Is Approved for Metastatic Triple-negative Breast Cancer

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The U.S. Food and Drug Administration (FDA) has rejected Immunomedics’ application for accelerated approval of sacituzumab govitecan as third-line treatment for advanced triple-negative breast cancer (TNBC), the company announced. The ... Read more

January 23, 2019

Tinagl1 Protein Suppresses Triple-negative Breast Cancer Development in Mouse Study

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A naturally occurring protein, called Tinagl1, suppressed the growth and spread of triple-negative breast cancer (TNBC) in mice by simultaneously targeting two cancer-promoting molecular pathways, a study shows. The study, ... Read more

January 21, 2019

Phase 3 Trial of Oraxol for Metastatic Breast Cancer Is Fully Enrolled

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The Phase 3 trial assessing Athenex‘s Oraxol — an oral formulation of the chemotherapy paclitaxel — for the treatment of advanced breast cancer has completed its planned patient enrollment. The progression of ... Read more

January 18, 2019

Insight Into How Breast Cancers Evade Immune System Could Help in Developing Therapies, Study Says

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Classifying breast cancers based on the mechanisms they use to avoid the immune system could be useful for designing effective immunotherapies for breast cancer patients, a study shows. The study, ... Read more

January 16, 2019

Breast Cancer Risk Appears to Be Higher in Women Who Have Had Babies, Study Shows

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Women who have given birth have a higher risk of developing breast cancer, a risk that can persist for more than 20 years after childbirth, compared with women of the ... Read more

January 14, 2019

Phase 1b/2 Trial Testing Rebastinib/Chemo Combo in Advanced Cancer Patients Begins

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A Phase 1b/2 clinical trial testing rebastinib, in combination with the chemotherapy medication carboplatin, in adults with breast cancer and patients with other advanced or metastatic solid tumors has begun, ... Read more

January 11, 2019

Partial Breast Radiation Therapy May Effectively Prevent Cancer Relapse, Trial Shows

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Accelerated partial breast irradiation, a therapy that delivers higher doses of radiation over a shorter period of time and targets only the part of the breast where the tumor was ... Read more

January 9, 2019

FDA OKs Phase 2 Trial of AE37-Keytruda Combo in Metastatic Triple-negative Breast Cancer

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Generex Biotechnology is planning a Phase 2 trial to test a combination of its AE37 peptide vaccine and Keytruda (pembrolizumab) in patients with advanced triple-negative breast cancer, after the U.S. Food and Drug Administration ... Read more